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Grant support

Supported by grants from The Interministerial Science and Technology Committee (SAF2005-05096) ; The Carlos III Health Institute, National Scientific Research, Development and Technological Innovation Program Health Investigation Resources, co-financed by The European Regional Development Fund (projects: FIS10/00335, FIS13/02500, FIS16/00506, FIS19/00844, FIS 22/01314) ; The European Union Horizon 2020 Research and Innovation program (EPIBRAIN project) , funded by the Joint Programming Initiative " A Healthy Diet for a Healthy Life " (ERA HDHL) , JFA2 Nutrition and the Epigenome, Horizon 2020 grant agreement number 696300, with funding provided by The Spanish State Agency for Investigation (PCI2018-093098/AEI) . Pere Virgili Health Research Institute (IISPV-2010/21) ; Biomedical Research Networking Center for the Pathophysiology of Obesity (CIBERobn) ; Agency for Management of University and Research grants, Generalitat de Catalunya (Support to Research Groups: 2009-1237, 2014-332) ; and Italfarmaco S.A., Spain. Predoctoral research fellowship from the URV Marti - Franques program [to L.A.S.C] . The funders played no role of any sort in the design and execution of the study or the reporting and interpretation of the results.

Analysis of institutional authors

Santos-Calderon, Luis AAuthorRamos-Rodriguez, CarlaAuthorRojas-Gómez, AlejandraAuthorBallesteros, MonicaAuthorMurphy, Michelle MCorresponding Author

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November 26, 2024
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Article
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Folate and cobalamin status, indicators, modulators, interactions, and reference ranges from early pregnancy until birth: the Reus-Tarragona birth cohort study

Publicated to:American Journal Of Clinical Nutrition. 120 (5): 1269-1283 - 2024-11-01 120(5), DOI: 10.1016/j.ajcnut.2024.09.015

Authors: Santos-Calderon, Luis A; Cavalle-Busquets, Pere; Ramos-Rodriguez, Carla; Grifoll, Carme; Rojas-Gomez, Alejandra; Ballesteros, Monica; Ueland, Per M; Murphy, Michelle M

Affiliations

BeVital AS, Bergen, Norway - Author
CIBEROBN ISCIII, Madrid, Spain - Author
Inst Invest Sanitaria Pere Virgili, Tarragona, Spain - Author
Univ Hosp Joan XXIII, Unit Obstet & Gynecol, Tarragona, Spain - Author
Univ Hosp St Joan, Unit Obstet & Gynecol, Reus, Spain - Author
Univ Rovira i Virgili URV, Fac Med & Hlth Sci, Unit Prevent Med & Biostat, Reus, Spain - Author
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Abstract

Background: Folate and cobalamin status, although essential for pregnancy, are not routinely monitored in prenatal care. Objectives: To investigate folate and cobalamin status and determinants throughout pregnancy, in the absence of mandatory folic acid (FA) fortification. Methods: In a cohort study of 831 mothers recruited at < 12 gestational weeks (GW), plasma folate, total homocysteine (tHcy), cobalamin, holotranscobalamin (holoTC), methylmalonic acid (MMA), red blood cell folate (RBCF), and the combined cobalamin status indicator (cB12) were determined at

Keywords

CobalaminCordDietary-intakeFolateFolic-acid supplementationHolotranscobalaminHomocysteineMethylmalonic acidNeural-tube defectsPlasma folatePopulationPregnancPregnancyRecommendationRiskVitamin-b-12 statusWomen

Quality index

Bibliometric impact. Analysis of the contribution and dissemination channel

The work has been published in the journal American Journal Of Clinical Nutrition due to its progression and the good impact it has achieved in recent years, according to the agency WoS (JCR), it has become a reference in its field. In the year of publication of the work, 2024 there are still no calculated indicators, but in 2023, it was in position 10/112, thus managing to position itself as a Q1 (Primer Cuartil), in the category Nutrition & Dietetics. Notably, the journal is positioned above the 90th percentile.

Impact and social visibility

From the perspective of influence or social adoption, and based on metrics associated with mentions and interactions provided by agencies specializing in calculating the so-called "Alternative or Social Metrics," we can highlight as of 2025-08-02:

  • The use, from an academic perspective evidenced by the Altmetric agency indicator referring to aggregations made by the personal bibliographic manager Mendeley, gives us a total of: 27.
  • The use of this contribution in bookmarks, code forks, additions to favorite lists for recurrent reading, as well as general views, indicates that someone is using the publication as a basis for their current work. This may be a notable indicator of future more formal and academic citations. This claim is supported by the result of the "Capture" indicator, which yields a total of: 38 (PlumX).

With a more dissemination-oriented intent and targeting more general audiences, we can observe other more global scores such as:

  • The Total Score from Altmetric: 1.
  • The number of mentions on the social network X (formerly Twitter): 1 (Altmetric).

It is essential to present evidence supporting full alignment with institutional principles and guidelines on Open Science and the Conservation and Dissemination of Intellectual Heritage. A clear example of this is:

  • The work has been submitted to a journal whose editorial policy allows open Open Access publication.
  • Assignment of a Handle/URN as an identifier within the deposit in the Institutional Repository: http://hdl.handle.net/20.500.11797/imarina9392511

Leadership analysis of institutional authors

This work has been carried out with international collaboration, specifically with researchers from: Norway.

There is a significant leadership presence as some of the institution’s authors appear as the first or last signer, detailed as follows: First Author (Santos Calderón, Luis Adolfo) and Last Author (Murphy, Michelle).

the author responsible for correspondence tasks has been Murphy, Michelle.